Zepbound week by week

Zepbound, milestone by milestone

1. Days 1-7

   First weekly injection at 2.5 mg. Early appetite reduction reported by some users within 48 hours. No significant weight change yet.

2. Weeks 2-4

   Satiety changes more pronounced. Users typically lose 2-4 lbs by week 4 on starting dose.

3. Weeks 4-16

   Titration through 5 → 7.5 → 10 → 12.5 mg. Weight loss accelerates. SURMOUNT-1 cohort lost ~10% by week 16.

4. Months 4-9

   Maintenance at 10, 12.5, or 15 mg. SURMOUNT-1 averaged 15-22% by month 9 depending on dose.

5. Month 12+

   SURMOUNT-1 averaged 20.9% at 72 weeks on 15 mg. Maintenance phase begins.