Question 1

How much does tirzepatide cost without insurance?

Accepted Answer

Tirzepatide is sold under brand names (Zepbound $1,349/month; Mounjaro $1,025/month). Manufacturer direct cash-pay through LillyDirect direct cash-pay is lower — $549/month for Zepbound.

Question 2

How much does Zepbound cost without insurance?

Accepted Answer

$1,349/month at retail. LillyDirect direct cash-pay reduces this to $549/month maintenance dose or $399/month for the 2.5mg starter dose. Compounded tirzepatide via telehealth runs $249–$349/month but is not FDA-approved.

Question 3

How much does Zepbound cost with insurance?

Accepted Answer

If covered with PA, $25–$150/month. Lilly savings card brings this to $25/month for commercially insured patients (12-month limit). The OSA-with-obesity FDA indication unlocks coverage on plans that don't cover weight-loss tirzepatide alone.

Question 4

Is Zepbound cheaper than Wegovy?

Accepted Answer

For cash-pay: yes — LillyDirect ($399 starter / $549 maintenance) is cheaper than NovoCare ($499/month). For insurance: similar copays ($25–$150). For compounded: tirzepatide compounded ($249–$349) costs more than semaglutide compounded ($199).

Question 5

Can I get Zepbound for $25/month?

Accepted Answer

Yes — if you have commercial insurance with Zepbound coverage and use the Lilly savings card. $25/month copay applies up to 12 months from card activation. After 12 months, copay reverts to your plan's standard tier copay.

How much does tirzepatide cost?

Tirzepatide price by brand (2026)

How much does tirzepatide cost?

Tirzepatide price by brand (2026)

Brand	Retail cash	Manufacturer direct	With insurance	Details
Zepbound	$1,349/month	$549/month	$25/month	Zepbound cost →
Mounjaro	$1,025/month	$549/month	$25/month	Mounjaro cost →