GLP-1 receptor agonist
Semaglutide: brands, cost & how it works
Semaglutide is a once-weekly GLP‑1 receptor agonist sold as Wegovy for chronic weight management and Ozempic for type 2 diabetes, plus an oral form (Rybelsus). It mimics the GLP‑1 hormone to curb appetite and slow gastric emptying; in the STEP 1 trial Wegovy produced about 14.9% average weight loss at 68 weeks.
The brands
Semaglutide brands compared
Semaglutide is the same molecule across every brand below — the differences are the FDA-approved indication, dose range, and price. Scored on efficacy, safety, cost, and access.
- Top pick1#1· Editor's ChoiceEditor's ChoiceBest for CV Risk
FDA-approved semaglutide for chronic weight management
Most transparent pricing—/10Editorial scoreiEditorial score — our drug ranking, weighted for clinical outcome (effectiveness and safety lead). Telehealth services also carry a separate Service scorecard (shown on the services pages), so the same brand can show a different number there.See offer →True cost · maint.$499/mo · 2.4mg - 2
- 3Also great