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Pharmacogenomics + microbiome + CGM + labs + body composition. Three tiers (minimal $149 / standard $497 / comprehensive $996) covering pre-GLP-1 workup. First aggregator of DTC test stack for GLP-1.
First aggregated DTC concierge for GLP-1 pre-treatment
Most patients start GLP-1 with zero workup. Better outcomes if you test first: pharmacogenomic prediction guides drug selection, baseline labs catch contraindications, body composition baseline tracks sarcopenia. We aggregate 9 DTC tests into 3 budget tiers.
Just the essentials. Baseline labs are non-negotiable before GLP-1 — skip everything else if budget tight.
Includes
Baseline labs + pharmacogenomic prediction + body composition trend. Best value: covers efficacy expectations, side-effect risk, sarcopenia prevention.
Includes
Maximum data per dollar. Includes microbiome + CGM for ongoing diet optimization during treatment. Worth it for patients planning long-term GLP-1 use (12+ months).
Includes
23andMe
April 2026 Nature study report — predicts GLP1R + GIPR variant response. Estimates weight-loss + nausea risk before treatment starts.
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Nucleus
Whole-genome interpretation includes GLP1R/GIPR variants + broader pharmacogenomic markers (CYP2D6, CYP2C19) affecting concomitant meds.
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Genomelink
Uses existing 23andMe/AncestryDNA raw data to add GLP-1 specific interpretation. Cheapest pharmacogenomic option if you already have DNA test.
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Viome
Gut microbiome composition correlates with GLP-1 response. Akkermansia muciniphila + specific bacterial ratios predict whether you'll be a strong vs weak responder.
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ZOE
Microbiome + blood-fat + blood-sugar response testing. Helps optimize diet during GLP-1 treatment — different foods spike blood sugar variably even on same medication.
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Abbott (Lingo)
Continuous glucose tracking. On GLP-1, food responses change dramatically — Lingo shows which foods still spike glucose vs which the medication blunted.
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Signos
FDA-cleared for weight management (Aug 2025). Pairs CGM data with AI coaching specifically for weight loss — useful adjunct to GLP-1 protocol.
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Personalabs
Bundled CMP + A1C + lipid + TSH + lipase baseline. Required before GLP-1 initiation. Cheaper than telehealth bundles for self-pay patients.
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DEXAFit / BodySpec
Baseline + 6-month DEXA scan measures lean mass loss. Critical because 40% of GLP-1-induced weight loss is muscle without resistance training intervention.
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No. Baseline labs are essential. Pharmacogenomics is high-value if you can afford ($199 23andMe). Microbiome + CGM are nice-to-have but add cost. Body composition (DEXA) matters at 6-month follow-up to catch sarcopenia. Pick your tier based on budget + commitment.
Standard labs sometimes (CMP, A1C, lipid, TSH) — if your prescriber orders them, insurance often pays. Pharmacogenomic tests rarely covered (considered investigational). Microbiome + CGM never covered for non-diabetic users. Self-pay is reality for most tests.
Both valid CGM options. Levels Health ($199/mo) bundles CGM + coaching. Veri ($150/mo) similar. Lingo ($49 per 14-day sensor) is cheapest. For GLP-1 monitoring specifically, all three work — Lingo wins on cost-per-day.
Before. Baseline labs prevent missing pre-existing issues. Pharmacogenomic prediction informs drug selection. Body composition baseline = sarcopenia tracking later. After-the-fact testing has less value.
Most pharmacogenomic results integrate into clinical workflow easily — bring printed report to appointment. Microbiome reports more contested clinically. CGM data is straightforward (glucose graphs). DEXA scan reports are standard medical format.
Educational tool, not diagnostic. DTC tests have varying clinical validation. Pharmacogenomics most rigorous. Microbiome science evolving. Discuss results with your prescriber before treatment decisions. Affiliate disclosure: links may earn commission.