Foundayo (orforglipron) dosage and titration schedule

Dose titration schedule

Foundayo (orforglipron) titrates through 6 steps — 0.8mg → 2.5mg → 5.5mg → 9mg → 14.5mg → 17.2mg — with most patients holding each step for about 4 weeks before increasing, and moving up only if the current dose is tolerated. The first step is for starting, not maintenance; the highest dose is 17.2mg.

1. 1
   0.8mg

   Weeks 1–4
2. 2
   2.5mg

   Weeks 5–8
3. 3
   5.5mg

   Weeks 9–12
4. 4
   9mg

   Weeks 13–16
5. 5
   14.5mg

   Weeks 17–20
6. 6
   17.2mg

   Weeks 21–24

How to take Foundayo (orforglipron)

• Administration: oral
• Prescription required.
• FDA status: approved.

Missed dose

If you miss a dose by less than 5 days (for weekly GLP-1) or 12 hours (for daily), take it as soon as possible. If more time has passed, skip and resume on your normal schedule — never double up. Always confirm with your prescriber.

Tips during titration

• Smaller, slower meals during the first 2–4 weeks of each step up
• Hydrate aggressively — GI side effects are worsened by dehydration
• If nausea is severe, your prescriber may pause at a lower dose longer

Frequently asked questions