Products from Eli Lilly
- Top pick1
Editor's ChoiceEli Lilly oral tirzepatide for weight loss (Apr 2026 launch)
- Highest efficacy oral GLP-1 — approaches injection tirzepatide levels
- More flexible dosing (no strict empty-stomach window)
- Same dual GIP/GLP-1 mechanism as Zepbound
FDA-approvedBrand-nameDaily oral tabletDual GIP / GLP-1Insurance eligible - 2
Runner-upEditor's ChoiceFDA-approved tirzepatide for weight loss
- Highest reported weight loss of any approved GLP-1 (avg ~21% in SURMOUNT-1)
- Dual GIP + GLP-1 mechanism
- FDA-approved for OSA + obesity (2024)
FDA-approvedBrand-nameOnce-weekly injectionDual GIP / GLP-1Insurance eligible - 3
Also greatTirzepatide for type 2 diabetes
- Significant A1C reduction
- Substantial weight loss as side benefit
Off-label useOnce-weekly injectionDual GIP / GLP-1Insurance eligible