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Wegovy substantially outperforms. STEP-1 trial: 15% weight loss vs phentermine ~5% historical. Wegovy is also long-term safe; phentermine restricted к short-term use.
Wegovy substantially outperforms. STEP-1 trial: 15% weight loss vs phentermine ~5% historical. Wegovy is also long-term safe; phentermine restricted к short-term use.
Phentermine (Adipex-P) is a stimulant suppressant approved for short-term use (typically 12 weeks). Average weight loss: 3-5% body weight. Limitations: cardiovascular side effects (hypertension, palpitations), tolerance development, abuse potential. Wegovy delivers 3x the weight loss long-term, no abuse potential, cardiovascular benefit instead of risk. Cost asymmetry: phentermine ~$40/month generic, Wegovy $25/month с insurance или $499 via NovoCare. For commercial-insurance patients: Wegovy is the clear better choice. For uninsured cash-pay patients seeking short-term jumpstart: phentermine may bridge until insurance approval.